Using stents to prevent a heart attack is a very common medical practice. Many a times, stent implantation can lead to blood clotting or might lead to arteries getting narrowed. This occurs, though stents are designed to do the opposite.

Recently clinical trials have suggested that Viagra can lead to a 30% reduction in blood clots after stent surgery.

Stents are basically tiny tubes made of metal mesh that are inserted in the arteries which are clogged to allow blood to flow easily by unclogging the arteries. In many cases stents are covered with drugs in order to prevent these blood vessels from closing. These are commonly referred to as drug-eluting stents. Though the design is precisely and practically made, these stents can often lead to some complications, the best example being: despite anti-clogging treatment, clots might develop near the stents.

Many recent researchers have found that coating stents with medicines such as Viagra which are primarily used for treating erectile dysfunction (ED) may reduce the chances of clotting after a stent surgery.

Viagra is a drug which is the most used when it comes to treating ED in men. It is a PDE5 inhibitor by classification. Sildenafil Citrate is its active ingredient. It is an FDA approved medication which is safe and effective to be used.

Sildenafil Citrate before being used and developed to treat ED was actually a drug used to help manage hypertension. The drug is nowadays sold as either Viagra or Revatio. The former being a medicine used in treating ED and the latter to treat pulmonary arterial hypertension. Sildenafil, this drug can increase the flow of blood and cause dilation of the arteries. As it can cause a dilation of the arteries it helps a great deal to reduce the blood clotting post stent surgery.

It is also seen that Viagra or lets refer to the active ingredient Sildenafil Citrate increases the activity of an enzyme known as protein kinase G (PKG). This enzyme prevents the walls of the arteries to thicken after an injury occurs. This somehow helps to avoid the complication caused by a stent placement surgery.

It is seen that when stent placement is done, the PKG enzyme is lowered which causes the arteries to thicken. Sildenafil, in this case causes an activation and increases the level of enzyme PKG which prevents this from happening. Therefore Viagra is an ideal drug for coating drug-elicit stents or in some cases best given orally after stent implantation. 

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